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Aflatoxin B 1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus.It is a very potent carcinogen with a TD 50 3.2 μg/kg/day in rats. [4] This carcinogenic potency varies across species with some, such as rats and monkeys, seemingly much more susceptible than others.
Aflatoxin M 1 is present in the fermentation broth of Aspergillus parasiticus, but it and aflatoxin M 2 are also produced when an infected liver metabolizes aflatoxin B 1 and B 2. Aflatoxin B 1 and B 2 (AFB), produced by A. flavus and A. parasiticus; Aflatoxin G 1 and G 2 (AFG), produced by some Group II A. flavus and Aspergillus parasiticus [19]
A. parasiticus produces aflatoxins B1, B2, G1, and G2, named for the colours emitted under UV light on thin-layer chromatography plates—either blue and green. The numbers refer to the type of compound with 1 being major and 2 being minor. [3] These aflatoxins are carcinogenic mycotoxins which have detrimental effects to humans and livestock. [4]
Aflatoxin B 1 exo-8,9-epoxide is a toxic metabolite of aflatoxin B 1. It's formed by the action of cytochrome P450 enzymes in the liver. [1] In the liver, ...
The four major aflatoxins produced are B1, B2, G1, and G2. The production of the major toxins is a result of particular strains of A. flavus. Aflatoxin B1 is the most toxic and potent hepatocarcinogenic natural compound characterized.
Aflatoxin B1 is the most potent natural carcinogen known [9] and is usually the major aflatoxin produced by toxigenic strains. It is also the best studied: in a large percentage of the papers published, the term aflatoxin can be construed to mean aflatoxin B1. However, well over a dozen other aflatoxins (e.g., P1.
Aflatoxin B1; Aflatoxin B1 exo-8,9-epoxide; Aflatoxin M1; Aflatoxin total synthesis; T. Turkey X disease This page was last edited on 27 July 2019, at 11:09 (UTC). ...
Aspergillus parvisclerotigenus is a species of fungus in the genus Aspergillus.It is from the Flavi section. [2] The species was first described in 2005. [1] A. parvisclerotigenus has been isolated in Nigeria and has been found to produce aflatoxin B1, aflatoxin B2, aflatoxin G1, aflatoxin G2, aflatrem, aflavarin, aspirochlorin, cyclopiazonic acid, kojic acid, and paspaline.
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