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Fibromyalgia is a medical syndrome that causes chronic widespread pain, accompanied by fatigue, awakening unrefreshed, and cognitive symptoms.Other symptoms can include headaches, lower abdominal pain or cramps, and depression. [9]
Sensory overload, [11] emotional distress, injury, sleep deprivation, infections, and spending too long standing or sitting up are other potential triggers. [6] The resulting symptoms are disproportionate to the triggering activity and are often debilitating, potentially rendering someone housebound or bedbound until they recover.
[10]: 6 Extended periods of PEM, commonly referred to as "crashes" or "flare-ups" by people with the illness, can lead to a prolonged relapse. [33]: 50 Unrefreshing sleep is a further core symptom. People wake up exhausted and stiff rather than restored after a night's sleep.
The condition is much more common in women than in men but is usually more serious and debilitating in men. Other associated conditions include obesity, diabetes, metabolic syndrome, arthritis, acne, and other inflammatory disorders. Early diagnosis of this disease is very important to decrease the number of flares, pain, and discomfort. [7]
Post-menopausal women under hormone replacement therapy have also reported symptoms of fibrocystic breast changes, indicating hormones may play a major role. [citation needed] This condition is an accumulative process, partly caused by the normal hormonal variation during a woman's monthly cycle.
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
One of the most prominent causes of Fibrous anklylosis is physical trauma. [4] After experiencing a severe physical injury, the body will try to recover by activating it's mensenchymal stromal cells (MSCs), a type of stem cells that can differentiate into different cells such as osteoblasts, chondrocytes, and other factors such as bone matrix/growth factors that are used to stimulate growth ...
Functional somatic syndrome (FSS) is any of a group of chronic diagnoses with no identifiable organic cause.This term was coined by Hemanth Samkumar. [citation needed] It encompasses disorders such as fibromyalgia, chronic widespread pain, temporomandibular disorder, irritable bowel syndrome, [1] lower back pain, tension headache, atypical face pain, non-cardiac chest pain, insomnia ...