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It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. [1] [2] They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity.
Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.
Phytoncides are a biologically active substance of plant origin that kills or inhibits growth and development of bacteria, microscopic fungi, and protozoa. Phytoncides play an important role in plant immunity and in the relationships between organisms within an ecosystem. [2] The ability to produce phytoncides is a quality common among plants.
Capsidiol is a phytoalexin produced by certain plants in response to pathogenic attack.. Phytoalexins are antimicrobial substances, some of which are antioxidative as well. They are defined not by their having any particular chemical structure or character, but by the fact that they are defensively synthesized de novo by plants that produce the compounds rapidly at sites of pathogen infection.
Adult plant resistance (APR) is a specialist term referring to quantitative resistance that is not effective in the seedling stage but is effective throughout many remaining plant growth stages. [ 43 ] [ 44 ] [ 42 ] The difference between adult plant resistance and seedling resistance is especially important in annual crops . [ 45 ]
An antimicrobial is an agent that kills microorganisms (microbicide) or stops their growth (bacteriostatic agent). [1] Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified ...
Some effectors are known to suppress host defense processes. This can include reducing the plant's internal signaling mechanisms or reduction of phytochemicals production. [8] Phytohormones are chemicals used by plants for signaling; pathogens can produce these to modify plant growth to their own advantage.
The key aspect of FDA's strategy is the request that animal drug sponsors (those who own the right to market the product) voluntarily work with FDA to revise the approved use conditions for their medically important antimicrobial drug products to remove production uses (such as growth enhancement or feed efficiency), and bring the remaining ...