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The chorionic villi are at first small and non-vascular. 13–15 days: trophoblast only [1] Secondary: The villi increase in size and ramify, while the mesoderm grows into them. 16–21 days: trophoblast and mesoderm [1] Tertiary: Branches of the umbilical artery and umbilical vein grow into the mesoderm, and in this way the chorionic villi are ...
In humans it is formed by extraembryonic mesoderm and the two layers of trophoblast that surround the embryo and other membranes; [1] the chorionic villi emerge from the chorion, invade the endometrium, and allow the transfer of nutrients from maternal blood to fetal blood.
The chorionic membrane is a fibrous tissue layer containing the fetal blood vessels. [4] Chorionic villi form on the outer surface of the chorion, which maximise surface area for contact with maternal blood. [4] The chorionic villi are involved in fetal-maternal exchange. [10]
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
The form of the human placenta is generally classified as a discoid placenta. Within this, the cotyledons are the approximately 15-25 separations of the decidua basalis of the placenta, separated by placental septa. [3] Each cotyledon consists of a main stem of a chorionic villus as well as its branches and sub-branches. [3]
Histopathology of a chorionic villus, in a tubal pregnancy. The invasive lineage creates cytotrophoblasts that are essential in the process of implantation and forming a fully functional placenta. An undifferentiated cytotrophoblastic stem cell will differentiate into an extravillous cytotrophoblast intermediate and then into an interstitial ...
In developmental biology, choriogenesis is the formation of the chorion, an outer membrane of the placenta that eventually forms chorionic villi that allow the transfer of blood and nutrients from mother to fetus. [1]
In theory, CPM is when the trisomic cells are found only in the placenta. CPM is detected in approximately 1-2% of ongoing pregnancies that are studied by chorionic villus sampling (CVS) at 10 to 12 weeks of pregnancy. Chorionic villus sampling is a prenatal procedure which involves a placental biopsy.