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Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature of fibroblasts. The MEF is a limited cell line. After several transmissions, MEFs will senesce and finally die off.
The primary mouse embryonic fibroblast cells were transferred (the "T") every 3 days (the first "3"), and inoculated at the rigid density of 3 × 10 5 cells per 20 cm 2 dish (the second "3") continuously. [2] The spontaneously immortalized cells with stable growth rate were established after 20 to 30 generations in culture, and then named '3T3 ...
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14089 Ensembl ENSG00000078098 ENSMUSG00000000392 UniProt Q12884 P97321 RefSeq (mRNA) NM_001291807 NM_004460 NM_007986 RefSeq (protein) NP_001278736 NP_004451 NP_032012 Location (UCSC) Chr 2: 162.17 – 162.25 Mb Chr 2: 62.33 – 62.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that ...
A new study has identified a protein that helps drive bladder cancer by triggering the synthesis of cholesterol via mouse and cell models. ... cancer such as fibroblasts, which contribute to the ...
Female mice in the dangerous living environment group, showed higher levels of fecal corticosterone, and minimal maternal care compared to the females in the safe environment group. Furthermore, a dangerous environment inherently provides infanticide threats to female mice, increasing the likelihood that corticosterone concentrations will ...
Her work led to the ability to isolate permanent trophoblast stem cell lineages using fibroblast growth factor 4 (FGF4) in contact with mouse blastocysts or early postimplantation trophoblasts. These trophoblast lineages are crucial for the survival of the mammalian embryo in utero. [16] Rossant's work on mice lung tissue is also very significant.
UK Scientists successfully recreated and used a thousand-year-old Anglo Saxon remedy to kill hospital superbug MRSA. The Daily Telegraph said that the recipe calls for two species of Allium -- a ...
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