Search results
Results from the WOW.Com Content Network
Dantrolene sodium, sold under the brand name Dantrium among others, is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. [ 5 ] [ 6 ] [ 7 ] It achieves this by inhibiting Ca 2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors . [ 8 ]
Major adverse effects of dantrolene include general muscle weakness, sedation, and occasionally hepatitis. [5] Other common spasmolytic agents include: methocarbamol, carisoprodol, chlorzoxazone, cyclobenzaprine, gabapentin, metaxalone, and orphenadrine.
After weighing its questionable benefits against its possible adverse effects (including nausea, vomiting, muscle weakness and prolonged duration of action of nondepolarizing neuromuscular blocking agents [32]), experts no longer recommend the use of prophylactic dantrolene prior to trigger-free general anesthesia in MH-susceptible patients. [30]
Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [1] [7] Symptoms include high fever, confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [1]
Common side effects include low blood pressure, increased saliva production, muscle pain, and rash. [7] Serious side effects include malignant hyperthermia , hyperkalemia and allergic reactions . [ 8 ] [ 9 ] It is not recommended in people who are at risk of high blood potassium or a history of myopathy . [ 6 ]
The debate over whether people ages 60 and up should take aspirin continues as medical experts learn more about the potential pros and cons of long-term use.. Aspirin is an over-the-counter ...
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.