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bedinvetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in dogs; benazepril – ACE-inhibitor used in heart failure, hypertension, chronic kidney failure and protein-losing nephropathy; bethanechol – stimulates bladder contractions, tranquilizer, makes the patient feel no pain; bexagliflozin - oral antidiabetic ...
Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit factor Xa (Xa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.
tissue factor pathway inhibitor (TFPI) Y: bleeding with hemophilia: Cosfroviximab [28] ZMapp: mab: chimeric: ebolavirus glycoprotein: Ebola virus Cosibelimab [27] Unloxcyt [52] mab: human: Programmed death ligand-1 (PD-L1) Y: cutaneous squamous cell carcinoma: Crenezumab [32] mab: humanized: β-amyloid (1-40 and 1-42) Alzheimer's disease ...
Examples of Kunitz-type protease inhibitors are aprotinin (bovine pancreatic trypsin inhibitor, BPTI), Alzheimer's amyloid precursor protein (APP), and tissue factor pathway inhibitor (TFPI). Kunitz STI protease inhibitor, the trypsin inhibitor initially studied by Moses Kunitz, was extracted from soybeans. Standalone Kunitz domains are used as ...
Dirlotapide is a drug used to treat obesity in dogs. [1] It is manufactured by Pfizer and Zoetis and marketed under the brand name Slentrol. [citation needed]It works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. [2]
"INHIBITORS, INDUCERS AND SUBSTRATES OF CYTOCHROME P450 ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors". "MEDICATIONS METABOLIZED BY CYTOCHROME P450 3A4" (PDF)
Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
Tissue factor pathway inhibitor 2 is a protein that in humans is encoded by the TFPI2 gene. [5] [6] [7] References Further reading. This page was last edited on 4 ...
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