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  2. Hydrogen–deuterium exchange - Wikipedia

    en.wikipedia.org/wiki/Hydrogen–deuterium_exchange

    The exchange reaction can be followed using a variety of methods (see Detection). Since this exchange is an equilibrium reaction, the molar amount of deuterium should be high compared to the exchangeable protons of the substrate. For instance, deuterium is added to a protein in H 2 O by diluting the H 2 O solution with D 2 O (e.g. tenfold ...

  3. Deuterated drug - Wikipedia

    en.wikipedia.org/wiki/Deuterated_drug

    The concept of replacing hydrogen with deuterium is an example of bioisosterism, whereby similar biological effects to a known drug are produced in an analog designed to confer superior properties. [5]

  4. Pasteur effect - Wikipedia

    en.wikipedia.org/wiki/Pasteur_effect

    First, glucose metabolism is faster through ethanol fermentation because it involves fewer enzymes and limits all reactions to the cytoplasm. Second, ethanol has bactericidal activity by causing damage to the cell membrane and protein denaturing , allowing yeast fungus to outcompete environmental bacteria for resources. [ 6 ]

  5. Sulfate-reducing microorganism - Wikipedia

    en.wikipedia.org/wiki/Sulfate-reducing_microorganism

    Desulfovibrio vulgaris is the best-studied sulfate-reducing microorganism species; the bar in the upper right is 0.5 micrometre long.. Sulfate-reducing microorganisms (SRM) or sulfate-reducing prokaryotes (SRP) are a group composed of sulfate-reducing bacteria (SRB) and sulfate-reducing archaea (SRA), both of which can perform anaerobic respiration utilizing sulfate (SO 2−

  6. Bacteria found in flagship hospital ‘not normal’, inquiry told

    www.aol.com/bacteria-found-flagship-hospital-not...

    The Scottish Hospitals Inquiry took evidence on Wednesday from Kathleen Harvey-Wood, who worked as a clinical scientist in the microbiology unit of the Queen Elizabeth University Hospital (QEUH ...

  7. Denitrification - Wikipedia

    en.wikipedia.org/wiki/Denitrification

    Terminal electron acceptor is a compound that gets reduced in the reaction by receiving electrons. Examples of anoxic environments can include soils, [11] groundwater, [12] wetlands, oil reservoirs, [13] poorly ventilated corners of the ocean and seafloor sediments. Furthermore, denitrification can occur in oxic environments as well.

  8. Drug discovery - Wikipedia

    en.wikipedia.org/wiki/Drug_discovery

    A 2007 report [57] found that of the 974 small molecule new chemical entities developed between 1981 and 2006, 63% were natural derived or semisynthetic derivatives of natural products. For certain therapy areas, such as antimicrobials, antineoplastics, antihypertensive and anti-inflammatory drugs, the numbers were higher.

  9. Superoxide dismutase - Wikipedia

    en.wikipedia.org/wiki/Superoxide_dismutase

    Irwin Fridovich and Joe McCord at Duke University discovered the enzymatic activity of superoxide dismutase in 1968. [5] SODs were previously known as a group of metalloproteins with unknown function; for example, CuZnSOD was known as erythrocuprein (or hemocuprein, or cytocuprein) or as the veterinary anti-inflammatory drug "Orgotein". [6]