Search results
Results from the WOW.Com Content Network
The exchange reaction can be followed using a variety of methods (see Detection). Since this exchange is an equilibrium reaction, the molar amount of deuterium should be high compared to the exchangeable protons of the substrate. For instance, deuterium is added to a protein in H 2 O by diluting the H 2 O solution with D 2 O (e.g. tenfold ...
The concept of replacing hydrogen with deuterium is an example of bioisosterism, whereby similar biological effects to a known drug are produced in an analog designed to confer superior properties. [5]
The Trends series was established in 1976 with Trends in Biochemical Sciences, rapidly followed by Trends in Neurosciences, Trends in Pharmacological Sciences, and Immunology Today. Immunology Today, Parasitology Today, and Molecular Medicine Today changed their names to Trends in... in 2001. Drug Discovery Today was spun off as an independent ...
The quellung reaction has been used to identify the 93 known capsular serotypes of Streptococcus pneumoniae in diagnostic settings, but in recent years it has been challenged by the latex agglutination method, and further by molecular typing techniques such as the polymerase chain reaction, which detect DNA and therefore target genetic ...
Desulfovibrio vulgaris is the best-studied sulfate-reducing microorganism species; the bar in the upper right is 0.5 micrometre long.. Sulfate-reducing microorganisms (SRM) or sulfate-reducing prokaryotes (SRP) are a group composed of sulfate-reducing bacteria (SRB) and sulfate-reducing archaea (SRA), both of which can perform anaerobic respiration utilizing sulfate (SO 2−
Recent data suggest that iron-chelating molecules with similar properties to siderophores, were produced by marine bacteria under phosphate limiting growth condition. In nature phosphate binds to different type of iron minerals, and therefore it was hypothesized that bacteria can use siderophore-like molecules to dissolve such complex in order ...
The Scottish Hospitals Inquiry took evidence on Wednesday from Kathleen Harvey-Wood, who worked as a clinical scientist in the microbiology unit of the Queen Elizabeth University Hospital (QEUH ...
The Ugi reaction has been applied in combination with an intramolecular Diels-Alder reaction [16] in an extended multistep reaction. A reaction in its own right is the Ugi–Smiles reaction with the carboxylic acid component replaced by a phenol. In this reaction the Mumm rearrangement in the final step is replaced by the Smiles rearrangement. [17]