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A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1] [2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells . [ 2 ]
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocytes, or (2) nevus cells, a form of melanocyte that lack dendritic processes. [78] [79] Acral nevus (melanocytic nevus of acral skin, melanocytic nevus with intraepidermal ascent of cells) Amelanotic blue nevus (hypomelanotic blue nevus) Becker's nevus; Balloon ...
If a patient displays congenital melanocytic nevi or giant congenital melanocytic nevi, the criteria for diagnosis of neurocutaneous melanosis are as follows: [citation needed] Melanocytic deposits exist within the central nervous system that are either malignant or benign; The cutaneous lesions, giant or otherwise, are not malignant
Some genetic syndromes [30] including congenital melanocytic nevi syndrome which is characterized by the presence of nevi (birthmarks or moles) of varying size which are either present at birth, or appear within 6 months of birth. Nevi larger than 20 mm (3/4") in size are at higher risk for becoming cancerous. Chronic non-healing wounds. [30]
Nevi and melanomas are a group of neoplasia. Although a nevus and a melanoma are often treated as independent entities, there is evidence that a nevus can be a precursor for a melanoma. [1] Common mutations have been identified in nevi and melanomas. [2] [3] [4]
Giant congenital melanocytic nevus in newborn. Congenital melanocytic nevi may be divided into the following types: [6]: 690–1 Small-sized congenital melanocytic nevus is defined as having a diameter less than 2 cm (0.79 in). [6]: 690 Medium-sized congenital melanocytic nevus is defined as having a diameter more than 2 cm (0.79 in) but less ...
Melanocytic tumors are tumors developed from melanocytes. [1] [2] Types. Melanocytic nevus; Melanocytic tumors of uncertain malignant potential; Melanoma;