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Amygdalin (Laetrile) is a toxic drug that is not effective as a cancer treatment". Additionally, "No controlled clinical trials (trials that compare groups of patients who receive the new treatment to groups who do not) of laetrile have been reported." [24] The side effects of laetrile treatment are the symptoms of cyanide poisoning.
This was from the notion that depression was primarily due to norepinephrine deficits, partly based on the fact that drugs that relieve depression increase brain norepinephrine levels. [28] To date, a great number of potent and selective and mixed norepinephrine reuptake inhibitors (NRIs) have been marketed as antidepressants. [11]
[200] [201] This theory states that depression is due to an imbalance, most often a deficiency, of the monoamine neurotransmitters, namely serotonin, norepinephrine, and/or dopamine. [200] [201] However, serotonin in particular has been implicated, as in the serotonin hypothesis of depression. [202]
[122] [123] [124] For instance, a 2004 U.S. Food and Drug Administration (FDA) analysis of clinical trials on children with major depressive disorder found statistically significant increases of the risks of "possible suicidal ideation and suicidal behavior" by about 80%, and of agitation and hostility by about 130%. [125]
The depression is multifactorial and has been on the increase due to societal pressure, genetic association and increase in use of drugs (Zhang et al. 2016) [full citation needed]. incorporation of nursing in management of depression may seem important in that nursing hold a pivotal role in health care delivery where they are they are the ...
The drug is also under investigation as an antidepressant and for the treatment of neuropathic pain. It is related in chemical structure to venlafaxine. Due to being an opioid, there is risk of abuse and addiction, but it does have less abuse potential, respiratory depression, and constipation compared to other opioids (hydrocodone, oxycodone ...
Amphetamines are a drug used to commonly treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Past studies link amphetamine use to possibly developing the psychiatric disorder ...
Psychotic depression, also known as depressive psychosis, is a major depressive episode that is accompanied by psychotic symptoms. [2] It can occur in the context of bipolar disorder or major depressive disorder. [2]