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While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, isoflavonoids have the 3-phenylchromen-4-one backbone with no hydroxyl group substitution at position 2 (case of the isoflavones) or the 3-phenylchroman (isoflavan) backbone (case of isoflavanes, such as equol).
Isoflavones such as genistein and daidzein are found in a number of plants including lupin, fava beans, soybeans, kudzu, and psoralea being the primary food source, [4] [5] also in the medicinal plants, Flemingia vestita [6] and F. macrophylla, [7] [8] and coffee. [9] It can also be found in Maackia amurensis cell cultures. [10]
Isoflavone is an isomer of flavone, which is chromone substituted with a phenyl group in the 2-position. [1] In isoflavone, the phenyl group is in the 3-position. [1] [5] Substituted isoflavone derivatives are related to the parent by the replacement of two or three hydrogen atoms with hydroxyl groups. [1] Isoflavone, numbering.
Rotenone is an odorless, colorless, crystalline isoflavone. It occurs naturally in the seeds and stems of several plants, such as the jicama vine, and in the roots of several other members of the Fabaceae. It was the first-described member of the family of chemical compounds known as rotenoids.
Genistin is an isoflavone found in a number of dietary plants like soy and kudzu.It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. [1]
Daidzein and other isoflavones are produced in plants through the phenylpropanoid pathway of secondary metabolism and are used as signal carriers, and defense responses to pathogenic attacks. [2] In humans, recent research has shown the viability of using daidzein in medicine for menopausal relief, osteoporosis , blood cholesterol , and ...
Irilone is an isoflavone, a type of flavonoid. It can be found in Trifolium pratense (red clover), [1] in Iris unguicularis [2] and in Iris germanica. [3] References
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