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The S9 fraction is most frequently used in assays that measure the metabolism of drugs and other xenobiotics. It is defined by the U.S. National Library of Medicine 's " IUPAC Glossary of Terms Used in Toxicology" [ 1 ] as the " Supernatant fraction obtained from an organ (usually liver) homogenate by centrifuging at 9000 g for 20 minutes in a ...
The recommendation defines that a difference of one S-unit corresponds to a difference of 6 decibels (dB), equivalent to a voltage ratio of two, or power ratio of four. Signals stronger than S9 are given with an additional dB rating, thus "S9 + 20dB", or, verbally, "20 decibels over S9", or simply "20 over 9" (or even the simpler "20 over").
Thus, the outer diameter of a catheter in millimeters can be calculated by dividing the French size by 3. [2] For example, a catheter with a French size of 9 would have an outer diameter of approximately 3 mm. While the French scale aligns closely with the metric system, it introduces redundancy and the potential for rounding errors.
Last, multiply the original expression of the physical value by the fraction, called a conversion factor, to obtain the same physical value expressed in terms of a different unit. Note: since valid conversion factors are dimensionless and have a numerical value of one , multiplying any physical quantity by such a conversion factor (which is 1 ...
A metric prefix is a unit prefix that precedes a basic unit of measure to indicate a multiple or submultiple of the unit. All metric prefixes used today are decadic . Each prefix has a unique symbol that is prepended to any unit symbol.
The millimetre (SI symbol: mm) is a unit of length in the metric system equal to 10 −3 metres ( 1 / 1 000 m = 0.001 m). To help compare different orders of magnitude, this section lists lengths between 10 −3 m and 10 −2 m (1 mm and 1 cm). 1.0 mm – 1/1,000 of a meter; 1.0 mm – 0.03937 inches or 5/127 (exactly)
The study found significant differences between human liver microsomes and human liver S9 fractions in drug-metabolizing enzyme and transporter protein concentrations. The protein-protein correlations of these drug-metabolizing enzymes and transporters was determined relating to the two hepatic preparations.
The volume fraction coincides with the volume concentration in ideal solutions where the volumes of the constituents are additive (the volume of the solution is equal to the sum of the volumes of its ingredients). The sum of all volume fractions of a mixture is equal to 1: