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Low pressure baroreceptors have both circulatory and renal effects, which produce changes in hormone secretion. Stimulation of these receptors causes the atria to release atrial natriuretic peptide. This hormone acts on the kidneys to increase sodium excretion, which increases urine production and thereby leads to a decrease in blood pressure.
The low-pressure baroreceptors have both circulatory and renal effects; they produce changes in hormone secretion, resulting in profound effects on the retention of salt and water; they also influence intake of salt and water. The renal effects allow the receptors to change the mean pressure in the system in the long term.
Atrial volume receptors (also known as Veno-atrial stretch receptors [1]) are low pressure baroreceptors that are found in the atria of the heart. They are myelinated vagal fibres in the endocardium found at the junction between atria and the vena cava/pulmonary vein.
Flowchart showing baroreceptor reflex. The baroreflex or baroreceptor reflex is one of the body's homeostatic mechanisms that helps to maintain blood pressure at nearly constant levels. The baroreflex provides a rapid negative feedback loop in which an elevated blood pressure causes the heart rate to decrease. Decreased blood pressure decreases ...
Alpha 1 blockers inhibit vasoconstriction normally initiated by the baroreceptor reflex upon postural change and the subsequent drop in pressure. [26] Other antihypertensive medications may also cause orthostatic hypotension, in addition to anticholinergics , dopaminergic drugs, opiates and psychoactive medications .
The Bainbridge reflex (or Bainbridge effect or atrial reflex) is a cardiovascular reflex causing an increase in heart rate in response to increased stretching of the wall of the right atrium and/or the inferior vena cava as a result of increased venous filling (i.e., increased preload).
Baroreflex activation therapy is an approach to treating high blood pressure and the symptoms of heart failure. It uses an implanted device to electrically stimulate baroreceptors in the carotid sinus region. This elicits a reflex response through the sympathetic and vagal nervous systems that reduces blood pressure.
The carotid sinus baroreceptor can be oversensitive to manual stimulation from the pressure applied at the carotid sinus at the carotid bifurcation. It is a condition known as 'carotid sinus hypersensitivity' (CSH), 'carotid sinus syndrome' or 'carotid sinus syncope', in which manual stimulation causes large changes in heart rate and blood ...