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Hemagglutination, or haemagglutination, is a specific form of agglutination that involves red blood cells (RBCs). It has two common uses in the laboratory: blood typing and the quantification of virus dilutions in a haemagglutination assay .
A schematic diagram of the experimental setup to detect hemagglutination for blood typing. Hemagglutination blood typing detection: [24] This method consists of measuring the blood’s reflectance spectrum alone (non-agglutination), and that of blood mixed with antibody reagents (agglutination) using a waveguide-mode sensor. As a result, some ...
Hemagglutination is observed in the presence of staphylococci, vibrios, and other bacterial species, similar to the mechanism viruses use to cause agglutination of erythrocytes. [ 3 ] [ 4 ] The RBCs used in HA and HI assays are typically from chickens, turkeys, horses, guinea pigs, or humans depending on the selectivity of the targeted virus or ...
Hemagglutination is the process by which red blood cells agglutinate, meaning clump or clog. The agglutin involved in hemagglutination is called hemagglutinin . In cross-matching , donor red blood cells and the recipient's serum or plasma are incubated together.
Influenza hemagglutinin (HA) or haemagglutinin [p] (British English) is a homotrimeric glycoprotein found on the surface of influenza viruses and is integral to its infectivity.
The hemagglutination assay (HA) is a common non-fluorescence protein quantification assay specific for influenza. It relies on the fact that hemagglutinin , a surface protein of influenza viruses, agglutinates red blood cells (i.e. causes red blood cells to clump together).
Hemagglutination assay. Some viruses attach to molecules present on the surface of red blood cells, for example, influenza virus. [10] A consequence of this is that ...
Agglutinogen is an antigen [1] that causes the formation of agglutinins in the body and leads to agglutination, such as hemagglutination, which involves red blood cells (RBCs). The kind of agglutinogens present on the red blood cells helps determine the blood type of a person. [2]