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Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner. [1]
Phenotypic variation (due to underlying heritable genetic variation) is a fundamental prerequisite for evolution by natural selection. It is the living organism as a whole that contributes (or not) to the next generation, so natural selection affects the genetic structure of a population indirectly via the contribution of phenotypes.
A suppressor screen is used to identify suppressor mutations that alleviate or revert the phenotype of the original mutation, in a process defined as synthetic viability. [13] Suppressor mutations can be described as second mutations at a site on the chromosome distinct from the mutation under study, which suppress the phenotype of the original ...
A phenotypic trait is an obvious, observable, and measurable characteristic of an organism; it is the expression of genes in an observable way. An example of a phenotypic trait is a specific hair color or eye color. Underlying genes, that make up the genotype, determine the hair color, but the hair color observed is the phenotype.
Microsociology is one of the main levels of analysis (or focuses) of sociology, concerning the nature of everyday human social interactions and agency on a small scale: face to face. [ 1 ] : 5 Microsociology is based on subjective interpretative analysis rather than statistical or empirical observation, [ 2 ] : 18–21 and shares close ...
The sociology of culture is an older concept, and considers some topics and objects as more or less "cultural" than others. By way of contrast, Jeffrey C. Alexander introduced the term cultural sociology, an approach that sees all, or most, social phenomena as inherently cultural at some level. [3]
Sociobiology is a field of biology that aims to explain social behavior in terms of evolution.It draws from disciplines including psychology, ethology, anthropology, evolution, zoology, archaeology, and population genetics.
These are direct phenotypic benefits, sensory bias, the Fisherian runaway hypothesis, indicator traits and genetic compatibility. In the majority of systems where mate choice exists, one sex tends to be competitive with their same-sex members [ 4 ] and the other sex is choosy (meaning they are selective when it comes to picking individuals to ...