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Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]
In 1971 the Aikenhead family sold their chain to Molson, which later started a warehouse in 1991 to head off American chain The Home Depot. Molson sold their 75% stake to Home Depot in 1994, and it became the Canadian unit. [3] (Molson exited the hardware business with the sale of Beaver Lumber in 1999 to Home Hardware. Molson had acquired a ...
Muse is manufactured by InteraXon, a company based in Toronto, Ontario, Canada [2] that was founded in 2007 by Ariel Garten, Trevor Coleman, Chris Aimone, and Steve Mann originally at 330 Dundas Street West (Steve Mann's lab), in Toronto, Ontario, Canada.
In October 2008, St. Michael's was named one of Greater Toronto's Top Employers by Mediacorp Canada Inc., which was announced by the Toronto Star newspaper. [8] The hospital was also named one of the Best Employers for New Canadians for six consecutive years, from 2008 to 2013. [9] [10]
Chaperone-mediated autophagy (CMA) refers to the chaperone-dependent selection of soluble cytosolic proteins that are then targeted to lysosomes and directly translocated across the lysosome membrane for degradation.
Autophagy protein 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on chromosome 6.It is an E3 ubi autophagic cell death.ATG5 is a key protein involved in the extension of the phagophoric membrane in autophagic vesicles.
Autophagy-related protein 13 also known as ATG13 is a protein that in humans is encoded by the KIAA0652 gene. [5]ATG13 is an autophagy factor required for phagosome formation. . ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through phosphorylation of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 comp
As Canada's leader in defence and national security science and technology (S&T), DRDC maintains a broad scientific program and actively collaborates with industry, international allies, academia, other government departments and the national security community. DRDC Toronto and its forebears have made major contributions to knowledge and ...