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The main risk factors for osteoarthritis are age [2] [3] and body mass index, [4] [3] as such, OA is predominantly considered a disease of aging. [5] [6] As the body ages, catabolic factors begin to predominate over anabolic factors resulting in a reduction of extracellular matrix gene expression [7] and reduced cellularity [8] [7] in articular ...
More than 32.5 million adults in the United States have osteoarthritis and it becomes more common with age. Bone on bone: An overview of osteoarthritis types, risks and treatments Skip to main content
Shoulder arthritis is a clinical condition in which the joint that connects the ball of the arm bone (humeral head) to the shoulder blade socket (glenoid) has damaged or worn out cartilage. Normally the ends of the bone are covered with hyaline articular cartilage , a surface so smooth that the friction at the joint is less than that of an ice ...
Weight loss and exercise are the most safe and effective long-term treatments, in contrast to short-term treatments which usually have risk of long-term harm. [ 69 ] High impact exercise can increase the risk of joint injury, whereas low or moderate impact exercise, such as walking or swimming, is safer for people with osteoarthritis. [ 68 ]
Since being overweight is a risk factor for post-traumatic arthritis, lifestyle changes that help manage body weight are important in the treatment and prevention of the condition. Lifestyle changes and weight loss often involve educating the affected person about how to practice a healthy lifestyle. [21]
Shoulder replacement is a surgical procedure in which all or part of the glenohumeral joint is replaced by a prosthetic implant. Such joint replacement surgery generally is conducted to relieve arthritis pain or fix severe physical joint damage. [1] Shoulder replacement surgery is an option for treatment of severe arthritis of the shoulder joint.
Risk factors include bone fractures, joint dislocations, alcoholism, and the use of high-dose steroids. [1] The condition may also occur without any clear reason. [1] The most commonly affected bone is the femur (thigh bone). [1] Other relatively common sites include the upper arm bone, knee, shoulder, and ankle. [1]
A disease-modifying osteoarthritis drug (DMOAD) is a disease-modifying drug that would inhibit or even reverse the progression of osteoarthritis. [1] Since the main hallmark of osteoarthritis is cartilage loss, a typical DMOAD would prevent the loss of cartilage and potentially regenerate it.