Search results
Results from the WOW.Com Content Network
Outcomes research is a branch of ... the evaluation methodology of outcomes research may include both experimental and non-experimental designs: further, the ...
Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ...
In a classic 1966 paper, Avedis Donabedian, the renowned public health pioneer, described three distinct aspects of quality in health care: outcome, process and structure (in that order in the original paper). [15] He had misgivings about solely using outcomes as a measure of quality, but concluded that:
An evaluation which looks at the impact of an intervention on final welfare outcomes, rather than only at project outputs, or a process evaluation which focuses on implementation; An evaluation carried out some time (five to ten years) after the intervention has been completed so as to allow time for impact to appear; and
An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]
Outcome contains all the effects of healthcare on patients or populations, including changes to health status, behavior, or knowledge as well as patient satisfaction and health-related quality of life. Outcomes are sometimes seen as the most important indicators of quality because improving patient health status is the primary goal of healthcare.
Patient-reported outcomes are important in a regulatory context. The US Food and Drug Administration (FDA) has issued formal Guidance to Industry on PROs in label claims [24] and the European Medicines Agency (EMA) has produced a reflection paper on HRQoL. [25] Increasing numbers of regulatory submissions for new drugs provide PRO data to ...
However, the overall quality that is assigned to the recommendation is that of the evidence about effects on population-important outcomes. The higher the quality of evidence the more likely is a strong recommendation. Benefits and harms and burden: This requires an evaluation of the absolute effects of both the benefits and harms and their ...