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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
Depiction of smooth muscle contraction. Muscle contraction is the activation of tension-generating sites within muscle cells. [1] [2] In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. [1]
Temporal summation: When a single synapse inputs that are close together in time, their potentials are also added together. Thus, if a neuron receives an excitatory postsynaptic potential, and then the presynaptic neuron fires again, creating another EPSP, then the membrane of the postsynaptic cell is depolarized by the total sum of all the ...
In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. [a] The temporal sequence of action potentials generated by a neuron is called its "spike train". A neuron that emits an action potential, or nerve impulse, is often ...
The two ways that synaptic potentials can add up to potentially form an action potential are spatial summation and temporal summation. [5] Spatial summation refers to several excitatory stimuli from different synapses converging on the same postsynaptic neuron at the same time to reach the threshold needed to reach an action potential.
A fused tetanic contraction is the strongest single-unit twitch in contraction. [6] When tetanized, the contracting tension in the muscle remains constant in a steady state. This is the maximal possible contraction. [3] During tetanic contractions, muscles can shorten, lengthen or remain constant length. [7]
Therefore, in order to achieve threshold and generate an action potential, the postsynaptic neuron has the capacity to add up all of the incoming EPSPs based on the mechanism of summation, which can occur in time and space. Temporal summation occurs when a particular synapse is stimulated at a high frequency, which causes the postsynaptic ...
Temporal summation means that the effects of impulses received at the same place can add up if the impulses are received in close temporal succession. Thus the neuron ...