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The regulatory subunit dimer of PKA is important for localizing the kinase inside the cell. The dimerization and docking (D/D) domain of the dimer binds to the A-kinase binding (AKB) domain of A-kinase anchor protein (AKAP). The AKAPs localize PKA to various locations (e.g., plasma membrane, mitochondria, etc.) within the cell.
In computational biology, protein pK a calculations are used to estimate the pK a values of amino acids as they exist within proteins.These calculations complement the pK a values reported for amino acids in their free state, and are used frequently within the fields of molecular modeling, structural bioinformatics, and computational biology.
When PKAs receive energy greater than E d from bombarding electrons, they are able to displace more atoms, and some of the Frenkel defects become groups of interstitial atoms with corresponding vacancies, within a few interatomic distances of each other. In the case of bombardment by fast-moving atoms or ions, groups of vacancies and ...
This list of awards for contributions to society is an index to articles on notable awards for contributions to society. It excludes humanitarian and service awards , religion-related awards , peace prizes , law enforcement awards and honors and legal awards , which are covered by separate lists.
Carbonic acid equilibria are important for acid–base homeostasis in the human body. An amino acid is also amphoteric with the added complication that the neutral molecule is subject to an internal acid–base equilibrium in which the basic amino group attracts and binds the proton from the acidic carboxyl group, forming a zwitterion .
This list of global issues presents problems or phenomena affecting people around the world, including but not limited to widespread social issues, economic issues, and environmental issues. Organizations that maintain or have published an official list of global issues include the United Nations, and the World Economic Forum.
A tyrosine residue also plays an important role in photosynthesis. In chloroplasts (photosystem II), it acts as an electron donor in the reduction of oxidized chlorophyll. In this process, it loses the hydrogen atom of its phenolic OH-group. This radical is subsequently reduced in the photosystem II by the four core manganese clusters. [11]
You can take a human infant and place it into any kind of social order and it will function acceptably. What makes human society so distinctive is the fabulous range of quite different forms it takes across the world. Yet in any given society, the range of permitted behaviours is quite narrowly constrained.