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Ripretinib, sold under the brand name Qinlock, is a medication for the treatment of adults with advanced gastrointestinal stromal tumor (GIST), a type of tumor that originates in the gastrointestinal tract. [3] [4] It is taken by mouth. [3] [4] Ripretinib inhibits the activity of the kinases KIT and PDGFRA, which helps keep cancer cells from ...
Avapritinib, sold under the brand name Ayvakit among others, is a medication used for the treatment of advanced systemic mastocytosis and indolent systemic mastocytosis. It is also used for the treatment of tumors due to one specific rare mutation: it is specifically intended for adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) that harbor a platelet-derived growth ...
Image showing Gastrointestinal Stromal Tumor after surgical removal. For localized, resectable adult GISTs, if anatomically and physiologically feasible, surgery is the primary treatment of choice. [22]: 69 Surgery can be potentially curative, but watchful waiting may be considered in small tumors in carefully selected situations. [28]
Imatinib use may cause lightening/depigmentation or darkening/repigmentation of hair (as is the case with some other tyrosine kinase inhibitors) and/or skin as well as hyperpigmentation of the gingiva. The median onset of hair color change is 4 weeks after initiation of therapy (but may occur over a year after initiation), is dose-dependent ...
Oral minoxidil for hypertension, [13] [14] however topical minoxidil is a first-line drug for hair loss. Monoamine oxidase inhibitors — due to potentially lethal dietary and drug interactions which may trigger hypertensive crisis and/or serotonin syndrome , [ 15 ] they are generally used only when other classes of antidepressants (e.g., SSRIs ...
On the June 24, 2024 episode of her podcast “Let’s Be Clear,” the “Charmed” star, who was first diagnosed with breast cancer in 2015 and then diagnosed with stage 4 incurable breast ...
High-dose chemotherapy (HDC) is a regimen of chemotherapy medicines given at larger dosages. This therapeutic strategy is used to treat some cancers, especially those that are aggressive or have a high chance of coming back. With increased doses of chemotherapy chemicals administered to the body, HDC seeks to optimize the death of cancer cells.
Rapid cell replication is one of the hallmarks of cancer; however, hair follicle cells also grow and divide quickly. Consequently, the chemotherapy drugs usually inhibit hair growth. [16] The dose and type of medicine will determine the severity of hair loss. Once the course of chemotherapy has ended, new hair growth may begin after three to 10 ...