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People with severe neutropenia, a low neutrophil count, have an increased risk of developing serious infections. One of the approaches to preventing and treating infections in people with neutropenia is to increase the neutrophil count, which is commonly done using drugs like G-CSF to stimulate the production of neutrophils in the bone marrow. [6]
Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood. [4] Neutrophils make up the majority of circulating white blood cells and serve as the primary defense against infections by destroying bacteria, bacterial fragments and immunoglobulin-bound viruses in the blood. [5]
In gene therapy, a gene encoding for a certain protein is inserted into a vector. [11] The vector containing the therapeutic gene is then injected into the patient. [11] Once inside the body the vector introduces the therapeutic gene into host cells, and the protein encoded by the newly inserted gene is then produced by the body's own cells. [11]
According to the New York Times: "Changes in medicine have eliminated the need for millions of blood transfusions, which is good news for patients getting procedures like coronary bypasses and other procedures that once required a lot of blood." And, "Blood bank revenue is falling, and the decline may reach $1.5 billion a year this year [2014 ...
Its main uses are in intensive care medicine (pneumonia, peritonitis), some diabetes-related foot infections, and empirical therapy in febrile neutropenia (e.g., after chemotherapy). The drug is administered intravenously every 6 or 8 hr, typically over 3–30 min. It may also be administered by continuous infusion over four hours.
The therapy has a US list price of US$2.2 million. [18] The cost effectiveness threshold of the therapy in the US is estimated to be between $1.35 million and $2.05 million [19] depending on perspective (healthcare vs limited societal) and assuming the willingness to pay for 1 quality-adjusted life year (QALY) at $100,000–$150,000. [20]
The Solawave Radiant Renewal Wand is a red light therapy device that is best used daily when paired with your preferred serums to stimulate collagen, improve the appearance of fine lines and ...
[4] [12] [14] [17] [27] Therapeutic alternatives with similar clinical performance are listed for some medicines and they may be considered for national essential medicines lists. [17] [18] The 9th Essential Medicines List for Children was updated in July 2023. [23] [28] Note: An α indicates a medicine is on the complementary list. [4] [14] [17]