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Yohimbine (/ j oʊ ˈ h ɪ m b iː n /), [2] also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. Yohimbine is an α 2-adrenergic receptor antagonist, and has been used in a variety of research ...
yohimbine Pausinystalia johimbe: rapid heart rate, hypertension, hypotension, heart problems, death [4] Herbs with adverse drug interactions. Name Other common names
Yohimbine is an indole alkaloid and is an adrenoceptor antagonist. It affects the central nervous system, autonomic nervous system, and the penile tissue and vascular smooth muscle cells that are involved in penile erection and it is also used to treat physiologically impaired and psychogenic erectile dysfunction, [ 1 ] [ 4 ] preferably in ...
Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauvolfia and Corynanthe (including Pausinystalia). [1] It is a stereoisomer of yohimbine. [1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac. [1]
Set of medicinal plants including yohimbe. Corynanthe johimbe, synonym Pausinystalia johimbe, common name yohimbe, is a plant species in the family Rubiaceae native to western and central Africa (Nigeria, Cabinda, Cameroon, Congo-Brazzaville, Gabon, Equatorial Guinea). [1]
Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure. [1] It has been marketed under numerous brand names including Card-Lamuran, Circolene, Cristanyl, Duxil, Duxor, Hydroxysarpon, Iskedyl, Isosarpan, Isquebral, Lamuran, Melanex, Raunatin, Saltucin Co, Salvalion, and Sarpan. [1]
[3] [4] This is in contrast to yohimbine and rauwolscine which have around 30-fold higher affinity for the α 2-adrenergic receptor over the α 1-adrenergic receptor. [3] [4] As a result, corynanthine is not a stimulant (or an aphrodisiac for that matter), but a depressant, and likely plays a role in the antihypertensive properties of Rauvolfia ...
Alpha-2 blockers (or α 2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α 2 adrenergic receptor.They are mainly used in research, having found limited clinical application in human medicine.