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Atrophy of the hippocampus has been observed during depression, consistent with animal models of stress and neurogenesis. [116] [117] Stress can cause depression and depression-like symptoms through monoaminergic changes in several key brain regions as well as suppression in hippocampal neurogenesis. [118]
Poor diet in early childhood affects the number of neurons in parts of the brain. [1]Nutritional neuroscience is the scientific discipline that studies the effects various components of the diet such as minerals, vitamins, protein, carbohydrates, fats, dietary supplements, synthetic hormones, and food additives have on neurochemistry, neurobiology, behavior, and cognition.
Each macronutrient can impact cognition through multiple mechanisms, including glucose and insulin metabolism, neurotransmitter actions, oxidative stress and inflammation, and the gut-brain axis. [ 4 ] [ 5 ] [ 6 ] Inadequate macronutrient consumption or proportion could impair optimal cognitive functioning and have long-term health implications.
In plants and animals, mineral absorption, also called mineral uptake is the way in which minerals enter the cellular material, typically following the same pathway as water. In plants, the entrance portal for mineral uptake is usually through the roots. Some mineral ions diffuse in-between the cells. In contrast to water, some minerals are ...
Deficiency of magnesium can cause tiredness, generalized weakness, muscle cramps, abnormal heart rhythms, increased irritability of the nervous system with tremors, paresthesias, palpitations, low potassium levels in the blood, hypoparathyroidism which might result in low calcium levels in the blood, chondrocalcinosis, spasticity and tetany, migraines, epileptic seizures, [7] basal ganglia ...
Thus, a damaged hippocampus can cause memory loss and inability of cognitive function. Furthermore, as the hippocampus is the region controlling learning and memory processes, the research on Schaffer collaterals may help to find treatments for diseases related to the hippocampus or its neural processing pathways such as Alzheimer's disease , a ...
The forgetting curve hypothesizes the decline of memory retention in time. This curve shows how information is lost over time when there is no attempt to retain it. [1] A related concept is the strength of memory that refers to the durability that memory traces in the brain. The stronger the memory, the longer period of time that a person is ...
In most mammals, including humans, it only occurs in the subgranular zone of the hippocampus, and in the olfactory bulb. [1] The neurogenesis hypothesis of depression proposes that major depressive disorder is caused, at least partly, by impaired neurogenesis in the subgranular zone of the hippocampus. [2]