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The choice of liposome preparation method depends, i.a., on the following parameters: [38] [39] the physicochemical characteristics of the material to be entrapped and those of the liposomal ingredients; the nature of the medium in which the lipid vesicles are dispersed; the effective concentration of the entrapped substance and its potential ...
Lipid bilayer. This fluid lipid bilayer cross section is made up entirely of phosphatidylcholine. The three main structures phospholipids form in solution; the liposome (a closed bilayer), the micelle and the bilayer. The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.
The earliest model bilayer system developed was the “painted” bilayer, also known as a “black lipid membrane.” The term “painted” refers to the process by which these bilayers are made. First, a small aperture is created in a thin layer of a hydrophobic material such as Teflon. Typically the diameter of this hole is a few tens of ...
A thin film is a layer of material ranging from fractions of a nanometer (monolayer) to several micrometers in thickness. [1] The controlled synthesis of materials as thin films (a process referred to as deposition) is a fundamental step in many applications. A familiar example is the household mirror, which typically has a thin metal coating ...
Langmuir film consisting of complex phospholipids in liquid-condensed state floating on water subphase, imaged with a Brewster angle microscope.. A Langmuir–Blodgett (LB) film is an emerging kind of 2D materials to fabricate heterostructures for nanotechnology, formed when Langmuir films—or Langmuir monolayers (LM)—are transferred from the liquid-gas interface to solid supports during ...
Vesicle (biology and chemistry) Scheme of a liposome formed by phospholipids in an aqueous solution. In cell biology, a vesicle is a structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Vesicles form naturally during the processes of secretion (exocytosis), uptake (endocytosis), and the transport of ...
Stranski–Krastanov growth (SK growth, also Stransky–Krastanov or ' Stranski–Krastanow') is one of the three primary modes by which thin films grow epitaxially at a crystal surface or interface. Also known as 'layer-plus-island growth', the SK mode follows a two step process: initially, complete films of adsorbates, up to several ...
Advantages of SLNs include the use of physiological lipids (which decreases the danger of acute and chronic toxicity), the avoidance of organic solvents, a potential wide application spectrum (dermal, per os, intravenous) and the high pressure homogenization as an established production method.