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These consistently negative results have resulted in hydrazine sulfate being described as a "disproven cancer therapy" in a recent medical review. [20] Similarly, other reviews have concluded that there is "strong evidence" against the use of hydrazine sulfate to treat anorexia or weight loss in cancer patients. [31] [32]
Amygdalin (Laetrile) is a toxic drug that is not effective as a cancer treatment". Additionally, "No controlled clinical trials (trials that compare groups of patients who receive the new treatment to groups who do not) of laetrile have been reported." [24] The side effects of laetrile treatment are the symptoms of cyanide poisoning.
In vitro testing demonstrated that AOH1996 inhibited the growth and induced cell cycle arrest and apoptotic cell death in a wide variety of cancer cell lines, but had no effect on several normal, nonmalignant cell types. [6] [7] In mouse and dog animal models, there were no observed side effects or toxicity even at six times the effective dose. [3]
Cariporide targets and inhibits the Na + /H + exchanger (NHE) isoform 1, which is ubiquitously expressed and involved in pH regulation of the myocardium. [3] During myocardial ischemia, NHE activation leads to an influx of Na + and, upon reperfusion, reverses the Na + /Ca 2+ exchanger and results in an overload of intracellular Ca 2+. [4]
Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, [9] and germ cell tumors.
Camptothecin (CPT) is a topoisomerase inhibitor.It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs.It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used in traditional Chinese medicine.
He invented a method that, he said, could treat virtually all forms of cancer, [1] with no side effects, and without the need for surgery or medication. [1] [2] [3] [needs update] He also demonstrated a device that generated flammable hydrogen-containing gas from salt-water-solution by the use of radiowaves. In the media this was dubbed ...
Radioligand therapies for cancer treatment are not the first course of action and generally require the patient to have undergone other previous treatments and many diagnostic imagings (i.e. seeing if specific receptors/antigens exist) to determine the benefit vs. adverse effect of undergoing the radioligand therapy.
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