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Opioid-induced hypogonadism, caused by negative effect of opioids on hypothalamo-pituitary gonadal axis is most often ( 21-86% of opioid users). [6] Hypogonadism is induced through direct inhibitory action of opioids on receptors within the hypothalamic–pituitary–gonadal (HPG) and hypothalamic–pituitary–adrenal (HPA) axes as well as testosterone production within the testes. [6]
Irritable bowel syndrome, or IBS, is among the most common gastrointestinal conditions today. It affects some 10% to 15% of people in the U.S., per the American College of Gastroenterology. A ...
Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70] Common adverse reactions in patients taking opioids for pain relief include nausea and vomiting, drowsiness, itching, dry mouth, dizziness, and constipation.
Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [5] [4] It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease, short bowel syndrome, [4] Crohn's disease, and ulcerative colitis. [5]
Morphine can interfere with menstruation by suppressing levels of luteinizing hormone. Many studies suggest the majority (perhaps as many as 90%) of chronic opioid users have opioid-induced hypogonadism. This effect may cause the increased likelihood of osteoporosis and bone fracture observed in chronic morphine users. Studies suggest the ...
Certain conditions can affect the body's ability to synthesize or absorb vitamin D, such as liver disease, kidney disease and inflammatory bowel disease, Adamian adds. Medications that can lower ...
A fecal impaction or an impacted bowel is a solid, immobile bulk of feces that can develop in the rectum as a result of chronic constipation [1] (a related term is fecal loading which refers to a large volume of stool in the rectum of any consistency). [2]
It causes constipation and bloating. On listening to the abdomen with a stethoscope, no bowel sounds are heard because the bowel is inactive. [citation needed] It is a common side effect of some types of surgery, termed postsurgical ileus. It can also result from certain drugs and from various injuries and illnesses, such as acute pancreatitis.