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The effect of anabolic steroids on the heart can cause myocardial infarction and strokes. [5] Conditions pertaining to hormonal imbalances such as gynecomastia and testicular size reduction may also be caused by AAS. [6] In women and children, AAS can cause irreversible masculinization. [6]
The FDA has required that testosterone pharmaceutical labels include warning information about the possibility of an increased risk of heart attacks and stroke. [11] They have also required the label include concerns about abuse and dependence. [83] Injectable forms of testosterone can cause a lung problem called pulmonary oil microembolism (POME).
Excessive levels of testosterone in men may be associated with hyperandrogenism, higher risk of heart failure, increased mortality in men with prostate cancer, [7] and male pattern baldness. Testosterone is a steroid hormone from the androstane class containing a ketone and a hydroxyl group at positions three and seventeen respectively.
He had suffered a heart attack, according to an Instagram story Thorpe posted to Tippet’s page. It was not immediately clear if steroids played a role in his death. Turkish authorities did not ...
[6] [7] For most medical applications, an AAS with potent anabolic and minimal androgenic and cardiovascular effects would be an advantage. In the 1930s, 17α-alkylated anabolic steroids were discovered. These have increased metabolic stability and are orally active, but are not tissue selective. [8]
Although the use of anabolic steroids can sometimes cause enlargement and thickening of the left ventricle, Schwarzenegger was born with a congenital genetic defect in which his heart had a bicuspid aortic valve, a condition that rendered his aortic valve with two cusps instead of three, which can occasionally cause problems later in life. [27]
The classifications of substances as performance-enhancing substances are not entirely clear-cut and objective. As in other types of categorization, certain prototype performance enhancers are universally classified as such (like anabolic steroids), whereas other substances (like vitamins and protein supplements) are virtually never classified as performance enhancers despite their effects on ...
Biological Toxins such as Diphtheria toxin [18]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [19] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.
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