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2. Anti-allergic agent - Wikipedia

   en.wikipedia.org/wiki/Anti-allergic_agent

   Another type of antihistamines known as H2-antihistamines are used to treat gastrointestinal conditions caused by excessive stomach acid. [8] Mechanism. H-1 antihistamines work by inhibiting histamine from binding to H-1 receptors. Histamine receptors expressed in smooth muscles, vascular endothelial cells, the heart, and the central nervous ...

3. Sominex - Wikipedia

   en.wikipedia.org/wiki/Sominex

   A 2023 Forbes report on the use of diphenhydramine for canine allergies listed several brand names, including Benadryl and Sominex, noting that veterinarians will use the medicine off-label to treat dog allergies but that it has not been FDA approved for use in non-humans. [67]

4. Piperoxan - Wikipedia

   en.wikipedia.org/wiki/Piperoxan

   One of Bovet and Fourneau's students, Anne-Marie Staub, published the first structure–activity relationship (SAR) study of antihistamines in 1939. [1] Piperoxan and analogues themselves were not clinically useful due to the production of toxic effects in humans and were followed by phenbenzamine (Antergan) in the early 1940s, which was the ...

5. Clemastine - Wikipedia

   en.wikipedia.org/wiki/Clemastine

   Clemastine is an antihistamine with anticholinergic and sedative effects. Antihistamines competitively bind to histamine receptor sites, thus reducing the neurotransmitter's effects. [9] Effects of histamine (which are countered by antihistamines) include: Increased capillary permeability; Increased capillary dilatation; Edema (i.e., swelling ...

6. Histidine decarboxylase - Wikipedia

   en.wikipedia.org/wiki/Histidine_decarboxylase

   Typical antihistamines block specific histamine receptors, depending on what physiological purpose they serve. For example, diphenhydramine (Benadryl™), targets and inhibits the H1 histamine receptor to relieve symptoms of allergic reactions. [24] Inhibitors of histidine decarboxylase can conceivably be used as atypical antihistamines.

7. H1 antagonist - Wikipedia

   en.wikipedia.org/wiki/H1_antagonist

   H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.