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Peak levels of quetiapine occur 1.5 hours after a dose. [86] The plasma protein binding of quetiapine is 83%. [86] The major active metabolite of quetiapine is norquetiapine (N-desalkylquetiapine). [67] Quetiapine has an elimination half-life of 6 or 7 hours. [86] [7] [8] Its metabolite, norquetiapine, has a half-life of 9 to 12 hours.
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Drug regimen simplification: Adherence to medication therapy is inversely related to the frequency of dosing. [2] The antipsychotic quetiapine is typically dosed two to three times daily for the management of schizophrenia. [3] A simpler regimen would be a once daily administered antipsychotic. [1] For example, risperidone can be administered ...
Another method is "defined daily dose" (DDD), which is the assumed average dose of an antipsychotic that an adult would receive during long-term treatment. [15] DDD is primarily used for comparing the utilization of antipsychotics (e.g. in an insurance claim database), rather than comparing therapeutic effects between antipsychotics. [15]
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
A drug combination chart designed for harm reduction by TripSit [1] Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals.
In case reports, quetiapine has been abused in doses taken by mouth (which is how the drug is available from the manufacturer), but also crushed and insufflated or mixed with water for injection into a vein. [292] Olanzapine, another sedating second-generation antipsychotic, has also been misused for similar reasons. [292]
A serotonin antagonist, or serotonin receptor antagonist, is a drug used to inhibit the action of serotonin and serotonergic drugs at serotonin (5-HT) receptors. Types [ edit ]