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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
In the European Randomized Study of Screening for Prostate Cancer (ERSPC) initiated in the early 1990s, the researchers concluded that PSA-based screening did reduce the rate of death from prostate cancer but created a high risk of overdiagnosis, i.e., 1410 men would need to be screened and 48 additional cases of prostate cancer would need to ...
Several things can cause a high PSA, including prostatitis, benign prostate enlargement, or prostate cancer, Dr. Pohlman says. Recent ejaculation can also increase PSA, Dr. Eilber says. PSA ...
PAP immunohistochemical staining is often used with PSA (staining), by pathologists, to help distinguish poorly differentiated carcinomas.For example, poorly differentiated prostate adenocarcinoma (prostate cancer) and urothelial carcinoma (bladder cancer) may appear similar under the microscope, but PAP and PSA staining can help differentiate them; [7] prostate adenocarcinoma often stains ...
WASHINGTON (Reuters) - -Alcoholic drinks should carry a label warning consumers about their cancer risks, the U.S. Surgeon General said in an advisory on Friday, noting that their consumption ...
The death of a spouse can have a major impact on one's mental health. Each individual may respond to their spouse's death differently. After the death of a spouse, many widows began to take more prescription medications for mental health issues. [5] The mental health effects differ between men and women.
Mike Rinder, a former Scientologist turned outspoken critic of the organization who co-hosted the A&E series Leah Remini: Scientology and the Aftermath, has died.He was 69. The author and ...
In 1970, Art and Diane Linkletter won the 1970 Grammy Award for Best Spoken Word Recording for their record "We Love You, Call Collect". The record, which was released in November 1969—just a few weeks after her death—sold 275,000 copies in eight weeks, peaking at #42 on the Billboard Hot 100.
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