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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 5–10 days after exposure. Symptoms often include a rash, joint pain, fever, and lymphadenopathy. It is a type of hypersensitivity, specifically immune complex hypersensitivity .
Laboratory abnormalities include normal or mild decreases in serum C3, C4, and CH50 levels, and mild proteinuria. In contrast to true serum sickness, renal and hepatic involvement is rare. Significant decreases in serum C3, C4, and CH50, reported in the literature for true serum sickness, are rarely described in serum sickness–like reaction.
it is most often based on the specific, accurate, precise and timely determinations of the active and.or toxic forms of drugs in biological samples collected at the appropriate times in the correct containers (PK monitoring), or can employ the measurement of a biological perimeter as a surrogate or end-point marker of effect (PD monitoring) e.g ...
PACVs were first deployed to Vietnam in May 1966 as PACV Division 107, Task Force 116, where they were used by the Navy for riverine patrol missions in the Mekong Delta and on the Mekong River. [ 26 ] : 15 Often called "Pac Vees", they were armed with a .50 caliber machine gun mounted on a rotating platform in the front and two side-mounted M60 ...
Very common (>10% incidence) adverse effects include: Somnolence † (produces an intermediate degree of sedation compared to other atypical antipsychotics [4]) Akathisia † Fasting glucose increased † Nausea † Parkinsonism † Insomnia † † These are dose-dependent.
Seizure [Note 10] Agitation (restlessness) Stably and for life, alters natural processes in the biological systems of the mitochondria of the nervous system. [6] [7] Inhibits the efficiency of the electron transport chain. [8] [9] Pain at the injection site; Injection site abscess