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Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
Kratom overdose is a subject of concern in many countries because of the associated rising number of hospitalizations and deaths in which chronic kratom use is a contributing factor. [11] [16] According to clinical reviews, a kratom overdose can cause liver toxicity, seizures, coma, and death, [16] especially in combination with excessive ...
People report using kratom for a variety of reasons, including pain relief, fatigue and to help curb drug withdrawal symptoms, according to the National Institute on Drug Abuse.
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa, commonly known as kratom. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
This is sponsored content. Us Weekly is not endorsing the websites or products set forth below. The use of THC in any capacity may lead to health concerns and users should consult medical ...
Betel nut chewing, also called betel quid chewing or areca nut chewing, is a practice in which areca nuts (also called "betel nuts") are chewed together with slaked lime and betel leaves for their stimulant and narcotic effects, the primary psychoactive compound being arecoline.
In the Philippines, where it is most commonly known as sambong, Blumea balsamifera is used in traditional herbal medicine for the common cold and as a diuretic. [1] [2] [3] It is also used for infected wounds, respiratory infections, and stomach pains in Thai and Chinese folk medicine.
For many people, menthol produces a cooling sensation when inhaled, eaten, or applied to the skin, and mint plants have been used for centuries for topical pain relief and as a food flavoring. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation .