Search results
Results from the WOW.Com Content Network
Phage therapy also allows for the possibility of biofilm penetration in cases where antibiotics are ineffective due to the increased resistance of biofilm-forming pathogens. [9] One major drawback to phage therapy is the evolution of phage-resistant microbes which was seen in a majority of phage therapy experiments aimed to treat sepsis and ...
Phage therapy is the use of bacteriophages to treat bacterial infections. Bacteriophage treatment offers a possible alternative to conventional antibiotic treatments for bacterial infection. [55] It is conceivable that, although bacteria can develop resistance to phages, the resistance might be easier to overcome than resistance to antibiotics.
As it was more reliable and easier to use than phage therapy, it soon became the method of choice, despite side effects and problems with resistant bacteria. Phage therapy remained a common treatment in the states of the Soviet Union , though, until its deconstruction.
Phage therapy relies on the use of naturally occurring bacteriophages to infect and lyse bacteria at the site of infection in a host. Due to current advances in genetics and biotechnology these bacteriophages can possibly be manufactured to treat specific infections. [ 271 ]
Phage therapy has gained recent attention in the United States as an alternative to standard antibiotic therapy. [ 5 ] [ 6 ] [ 7 ] It has been in practice for just over 100 years in countries such as Russia and Georgia , but due to the recent clinical attention of antibiotic resistance , Western countries have slowly been integrating phage ...
The genome of bacteriophages residing in the gut in Type-2 diabetes patients have been shown to contain numerous genes implicated in disease development. [6] Total phage representation in the virome is higher in individuals with Cardiovascular disease than healthy controls, totaling 63% and 18% respectively. [ 6 ]
Phage therapy has been used for years in MRSA in eastern countries, and studies are ongoing in western countries. [ 146 ] [ 147 ] Host-directed therapeutics , including host kinase inhibitors, as well as antimicrobial peptides are under study as adjunctive or alternative treatment for MRSA.
Alpha-glucosidase inhibitors (AGIs) are oral anti-diabetic drugs used for diabetes mellitus type 2 that work by preventing the digestion of carbohydrates (such as starch and table sugar). They are found in raw plants/herbs such as cinnamon and bacteria (containing the inhibitor acarbose ).