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Methanol and its vapours are flammable. Moderately toxic for small animals – Highly toxic to large animals and humans (in high concentrations) – May be fatal/lethal or cause blindness and damage to the liver, kidneys, and heart if swallowed – Toxicity effects from repeated over exposure have an accumulative effect on the central nervous system, especially the optic nerve – Symptoms may ...
As little as 10 mL of pure methanol when drunk is metabolized into formic acid, which can cause permanent blindness by destruction of the optic nerve. 15 mL is potentially fatal, [1] although the median lethal dose is typically 100 mL (3.4 fl oz) (i.e. 1–2 mL/kg body weight of pure methanol). [4] Reference dose for methanol is 0.5 mg/kg/day. [9]
In chemistry, an alcohol (from Arabic al-kuḥl 'the kohl'), [2] is a type of organic compound that carries at least one hydroxyl (−OH) functional group bound to a saturated carbon atom. [3] [4] Alcohols range from the simple, like methanol and ethanol, to complex, like sugars and cholesterol. The presence of an OH group strongly modifies the ...
However, depending on pH and temperature, methanogenesis has been shown to use carbon from other small organic compounds, such as formic acid (formate), methanol, methylamines, tetramethylammonium, dimethyl sulfide, and methanethiol. The catabolism of the methyl compounds is mediated by methyl transferases to give methyl coenzyme M. [4]
Data obtained from Lange's Handbook of Chemistry, 10th ed. and CRC Handbook of Chemistry and Physics 44th ed. The annotation, d a°C/b°C, indicates density of solution at temperature a divided by density of pure water at temperature b known as specific gravity. When temperature b is 4 °C, density of water is 0.999972 g/mL.
Fomepizole, a drug that competitively inhibits alcohol dehydrogenase, can be used in the setting of acute methanol [60] or ethylene glycol [61] toxicity. This prevents the conversion of the methanol or ethylene glycol to its toxic metabolites (such as formic acid, formaldehyde, or glycolate).
Methanol fuel is an alternative biofuel for internal combustion and other engines, either in combination with gasoline or independently. Methanol (CH 3 OH) is less expensive to sustainably produce than ethanol fuel, although it is more toxic than ethanol and has a lower energy density than gasoline.
The osmol gap is typically calculated with the following formula (all values in mmol/L): = = ([+] + [] + []) In non-SI laboratory units: Calculated osmolality = 2 x [Na mmol/L] + [glucose mg/dL] / 18 + [BUN mg/dL] / 2.8 + [ethanol/3.7] [3] (note: the values 18 and 2.8 convert mg/dL into mmol/L; the molecular weight of ethanol is 46, but empiric data shows that it does not act as an ideal ...