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The phenotype of a homozygous dominant pair is 'A', or dominant, while the opposite is true for homozygous recessive. Heterozygous pairs always have a dominant phenotype. [ 11 ] To a lesser degree, hemizygosity [ 12 ] and nullizygosity [ 13 ] can also be seen in gene pairs.
A pedigree chart is a diagram that shows the occurrence of certain traits through different generations of a family, [1] [2] most commonly for humans, show dogs, and race horses. [ citation needed ] Definition
In a test cross, the individual in question is bred with another individual that is homozygous for the recessive trait and the offspring of the test cross are examined. [2] Since the homozygous recessive individual can only pass on recessive alleles, the allele the individual in question passes on determines the phenotype of the offspring. [3]
The difference in phenotype between the homozygous (CH/CH) and heterozygous (CH/ch) horse may be subtle, in that the coat of the homozygote may be a shade lighter, with less mottling. [36] Horses with the homozygous recessive genotype (ch/ch) are not affected by champagne. Champagne is now identifiable by DNA test.
Autosomal dominant-recessive inheritance is made possible by the fact that the individuals of most species (including all higher animals and plants) have two alleles of most hereditary predispositions because the chromosomes in the cell nucleus are usually present in pairs . Carriers can be female or male as the autosomes are homologous ...
A simple example to illustrate genotype as distinct from phenotype is the flower colour in pea plants (see Gregor Mendel). There are three available genotypes, PP (homozygous dominant), Pp (heterozygous), and pp (homozygous recessive). All three have different genotypes but the first two have the same phenotype (purple) as distinct from the ...
Cats homozygous and heterozygous for this gene display shortened and kinked tails. Cats homozygous for the gene tend to have shorter, more kinked tails. [2] This can be distinguished phenotypically from the Manx cat mutation by the presence of kinking in the tail, often forming what looks like a knot at the distal end of the tail.
Sickle-cell anaemia is found mostly in tropical populations in Africa and India.An individual homozygous for the recessive sickle hemoglobin, HgbS, has a short expectancy of life, whereas the life expectancy of the standard hemoglobin (HgbA) homozygote as well as heterozygote is normal (though heterozygote individuals will suffer periodic problems).
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