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  2. Prothrombin time - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_time

    The prothrombin time ratio is the ratio of a subject's measured prothrombin time (in seconds) to the normal laboratory reference PT. The PT ratio varies depending on the specific reagents used, and has been replaced by the INR. [3] Elevated INR may be useful as a rapid and inexpensive diagnostic of infection in people with COVID-19. [4]

  3. Partial thromboplastin time - Wikipedia

    en.wikipedia.org/wiki/Partial_thromboplastin_time

    The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood. A historical name for this measure is the Kaolin-cephalin clotting time ( KCCT ), [ 1 ] reflecting kaolin and cephalin as materials historically used in the test.

  4. Mixing study - Wikipedia

    en.wikipedia.org/wiki/Mixing_study

    The basic purpose of these tests is to determine the cause of prolongation of Prothrombin Time (PT), Partial Thromboplastin Time, or sometimes of thrombin time (TT). Mixing studies take advantage of the fact that factor levels that are 50 percent of normal should give a normal Prothrombin time (PT) or Partial thromboplastin time (PTT) result. [2]

  5. Clotting time - Wikipedia

    en.wikipedia.org/wiki/Clotting_time

    Clotting time is a general term for the time required for a sample of blood to form a clot, or, in medical terms, coagulate.The term "clotting time" is often used when referring to tests such as the prothrombin time (PT), activated partial thromboplastin time (aPTT or PTT), activated clotting time (ACT), thrombin time (TT), or Reptilase time.

  6. Thrombin time - Wikipedia

    en.wikipedia.org/wiki/Thrombin_time

    Normal values for thrombin time may be 12 to 14 seconds, [6] but the test has significant reagent variability. If batroxobin is used, the time should be between 15 and 20 seconds. Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality.

  7. Factor XIII deficiency - Wikipedia

    en.wikipedia.org/wiki/Factor_XIII_deficiency

    Bleeding manifestation with normal PT, aPTT, TT, BT, and CT is suspected as factor XIII Deficiency. Confirmatory test is urea lysis test. If clot is easily lysed in 5(M) urea solution then unstable clot and factor-XIII deficiency is confirmed.

  8. Bleeding time - Wikipedia

    en.wikipedia.org/wiki/Bleeding_time

    Bleeding time may be affected by platelet function, certain vascular disorders and von Willebrand Disease—not by other coagulation factors such as haemophilia.Diseases that may cause prolonged bleeding time include thrombocytopenia, disseminated intravascular coagulation (DIC), Bernard-Soulier disease, and Glanzmann's thrombasthenia.

  9. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    If a coagulation factor is part of the contact activation or tissue factor pathway, a deficiency of that factor will affect only one of the tests: Thus hemophilia A, a deficiency of factor VIII, which is part of the contact activation pathway, results in an abnormally prolonged aPTT test but a normal PT test. Deficiencies of common pathway ...