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  2. Thiazide - Wikipedia

    en.wikipedia.org/wiki/Thiazide

    The thiazide receptor is a sodium-chloride transporter that pulls NaCl from the lumen in the distal convoluted tubule. Thiazide diuretics inhibit this receptor, causing the body to release NaCl and water into the lumen, thereby increasing the amount of urine produced each day. [6] An example of a molecule that is chemically a thiazide but not ...

  3. Cyclopenthiazide - Wikipedia

    en.wikipedia.org/wiki/Cyclopenthiazide

    Thiazide diuretics increase the excretion of sodium and potassium ions and decrease the excretion of calcium ions and uric acid so they are contraindicated in patients with hyponatraemia, hypokalaemia, hypercalcaemia and hyperuricaemia. They are also contraindicated in patients with Addison's disease.

  4. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone, like other thiazide diuretics, may unmask latent diabetes mellitus or exacerbate gout, especially by interacting with medicines used to treat gout. In addition, thiazide diuretics, including metolazone, are sulfonamides; those with hypersensitivity to sulfonamides ("sulfa allergy") may also be allergic to metolazone. [4]

  5. Diuretic - Wikipedia

    en.wikipedia.org/wiki/Diuretic

    The thiazides and potassium-sparing diuretics are considered to be calcium-sparing diuretics. [6] The thiazides cause a net decrease in calcium lost in urine. [7] The potassium-sparing diuretics cause a net increase in calcium lost in urine, but the increase is much smaller than the increase associated with other diuretic classes. [7]

  6. Trichlormethiazide - Wikipedia

    en.wikipedia.org/wiki/Trichlormethiazide

    Although trichlormethiazide is used to treat hypertension, its hypotensive effects may not necessarily be due to its role as a diuretic. [1] Thiazides in general cause vasodilation by activating calcium-activated potassium channels in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. [1]

  7. Hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Hydrochlorothiazide

    Hydrochlorothiazide is also sometimes used to prevent osteopenia and treat hypoparathyroidism, [17] hypercalciuria, Dent's disease, and Ménière's disease. A low level of evidence, predominantly from observational studies, suggests that thiazide diuretics have a modest beneficial effect on bone mineral density and are associated with a ...

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