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Benzylpenicillin, also known as penicillin G (PenG [4]) or BENPEN, [5] is an antibiotic used to treat a number of bacterial infections. [6] This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus. [6] It is not a first-line agent for pneumococcal meningitis. [6]
It is in the penicillin and beta lactam family of medications. [4] It usually results in bacterial death. [4] Phenoxymethylpenicillin was first made in 1948 by Eli Lilly. [5]: 121 It is on the World Health Organization's List of Essential Medicines. [6] It is available as a generic medication. [4]
6-APA ((+)-6-aminopenicillanic acid) is a chemical compound used as an intermediate in the synthesis of β–lactam antibiotics. The major commercial source of 6-APA is still natural penicillin G . The semi-synthetic penicillins derived from 6-APA are also referred to as penicillins and are considered part of the penicillin family of antibiotics.
When phenoxyethanol or phenoxyacetic acid are added to the culture medium, the mould produces penicillin V as the main penicillin instead. [8] 6-Aminopenicillanic acid (6-APA) is a compound derived from penicillin G. 6-APA contains the beta-lactam core of penicillin G, but with the side chains stripped off; 6-APA is a useful precursor for ...
Dicloxacillin is insensitive to beta-lactamase (also known as penicillinase) enzymes secreted by many penicillin-resistant bacteria. The presence of the isoxazolyl group on the side chain of the penicillin nucleus facilitates the β-lactamase resistance, since they are relatively intolerant of side-chain steric hindrance .
Benzathine benzylpenicillin, also known as benzathine penicillin G (BPG), is an antibiotic medication useful for the treatment of a number of bacterial infections. [3] Specifically it is used to treat strep throat , diphtheria , syphilis , and yaws .
Pen-Strep (also known as penicillin-streptomycin) is a mixture of penicillin G and streptomycin that is widely used in mammalian cell culture media to prevent bacterial contamination. The solution contains 5,000 units of penicillin G (sodium salt) which acts as the active base, and 5,000 micrograms of streptomycin (sulfate) (base per milliliter ...
The usual dose by mouth is one capsule of 250 mg 4 times a day in adults and half the adult dose as a syrup for children under the age of 10 years but over 2. [4] For children below the age of 2 years, the oral dose is a quarter of the adult oral dose. [3] Ampicillin/flucloxacillin is taken orally about half an hour before food. [5]