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  2. Cerebral atherosclerosis - Wikipedia

    en.wikipedia.org/wiki/Cerebral_atherosclerosis

    Cerebral atherosclerosis is a type of atherosclerosis where build-up of plaque in the blood vessels of the brain occurs. Some of the main components of the plaques are connective tissue, extracellular matrix, including collagen, proteoglycans, fibronectin, and elastic fibers; crystalline cholesterol, cholesteryl esters, and phospholipids; cells such as monocyte derived macrophages, T ...

  3. Hypertension and the brain - Wikipedia

    en.wikipedia.org/wiki/Hypertension_and_the_brain

    In turn, the brain is more vulnerable to ischemic insults as there is a dysregulation in the supply of blood and oxygen. [19] More specifically, hypertension inflicts damage to small resistance arteries, which supply nutrients to the internal capsule, brainstem, thalamus, cerebellum, and basal ganglia, and cause cell death and tissue ...

  4. Collagen - Wikipedia

    en.wikipedia.org/wiki/Collagen

    Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and accounts for 6% of the weight to skeletal muscle. [4] The fibroblast is the most common cell creating collagen in ...

  5. Arterial stiffness - Wikipedia

    en.wikipedia.org/wiki/Arterial_stiffness

    The primary sites of end-target organ damage following an increase in arterial stiffness are the heart, the brain (stroke, white matter hyperintensities (WMHs)), the placenta, and the kidneys (age-related loss of kidney function). [21] Firstly, stiffened arteries compromise the Windkessel effect of the arteries. [22]

  6. Collagen, type IV, alpha 1 - Wikipedia

    en.wikipedia.org/wiki/Collagen,_type_IV,_alpha_1

    Collagen alpha-1(IV) chain (COL4A1) is a protein that in humans is encoded by the COL4A1 gene on chromosome 13. [ 5 ] [ 6 ] It is ubiquitously expressed in many tissues and cell types. [ 7 ] COL4A1 is a subunit of the type IV collagen and plays a role in angiogenesis . [ 8 ]

  7. Cerebral autoregulation - Wikipedia

    en.wikipedia.org/wiki/Cerebral_autoregulation

    lower body negative pressure; pharmaceutical methods to raise or lower blood pressure; The quantification depends on the experimental setup and can involve methods such as regression, cross-correlation, transfer function analysis or fitting mathematical models. Measuring and understanding cerebral autoregulation remains a big challenge.

  8. Accused CEO shooter Luigi Mangione complained about back pain ...

    www.aol.com/news/accused-ceo-shooter-luigi...

    The Ivy League grad accused of fatally shooting UnitedHealthcare CEO Brian Thompson reportedly detailed his health woes, including debilitating back pain and “brain fog,” in a series of Reddit ...

  9. Connective tissue - Wikipedia

    en.wikipedia.org/wiki/Connective_tissue

    The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. [2] Blood, and lymph are classed as specialized fluid connective tissues that do not contain fiber.

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