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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
This type of drug has a high affinity for hydroxyapatite [28] and stays in bone tissue for a long period of time, [29] with alendronate, it has a half-life of approximately ten years. [30] The risk of a patient having MRONJ after discontinuing this medication is unknown. [30]
Alendronic acid/colecalciferol, sold under the brand name Fosamax Plus D among others, is a medication for the treatment of osteoporosis in men or in postmenopausal women. [3] [2] [4] [6] Alendronic acid/colecalciferol was approved for use in the United States and in the European Union in 2005. [7] [5]
Vitamin D and calcium are essential for overall health, but don’t reduce the risk of falls or fractures in generally healthy older adults, according to a new draft recommendation from the US ...
"Before my surgery, I looked 10 years older," Soto says. "After the surgery and the healing process, I actually looked 10 years younger...and still do to this day. This is a 20-year difference in ...
[5] [10] [11] [12] Long-term treatment with bisphosphonates produces anti-fracture and bone mineral density effects that persist for 3–5 years after an initial 3–5 years of treatment. [ 2 ] The bisphosphonate alendronate reduces the risk of hip, vertebral, and wrist fractures by 35-39%; zoledronate reduces the risk of hip fractures by 38% ...
Three years ago, she also joked that contouring, aging and having darker hair were reasons why she looked different in the years since her television debut. "So sick of women commenting on my face ...
Alendronate, a common bisphosphonate drug, has a three carbon length side chain for example. [17] Risedronate has heterocyclic structure containing nitrogen. Heterocyclic nitrogen containing bisphosphonates have revealed better results in terms of activity compared to earlier bisphosphonates with nitrogen bound to carbon chain. Studies on ...