Search results
Results from the WOW.Com Content Network
Some areas of the brain, such as the hippocampus, have been found to highly express L1CAM into adulthood, though the exact reason for this has not been elucidated. Due to its involvement in neuronal development and axon guidance, it has been proposed that L1CAM and L1-family proteins may be useful therapeutics to treat tissue damage in the CNS.
Alzheimer's disease (AD) has been identified as a proteopathy: a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. [1] Amyloid beta is a short peptide that is an abnormal proteolytic byproduct of the transmembrane protein amyloid-beta precursor protein (APP), whose function is ...
Tau proteins are found more often in neurons than in non-neuronal cells in humans. One of tau's main functions is to modulate the stability of axonal microtubules. [11] [13] Other nervous system microtubule-associated proteins (MAPs) may perform similar functions, as suggested by tau knockout mice that did not show abnormalities in brain development – possibly because of compensation in tau ...
Piantino is the senior author of a new study that for the first time shows how the brain’s glymphatic system clears away these proteins, emphasizing the importance of lifestyle measures such as ...
The human brain requires nutrients obtained from the diet to develop and sustain its physical structure and cognitive functions. [1] [3] [4] Additionally, the brain requires caloric energy predominately derived from the primary macronutrients to operate. [1] [4] The three primary macronutrients include carbohydrates, proteins, and fats.
This bidirectional communication between astrocytes and neurons add complexity to brain signaling, with implications for brain function and neurological disorders. [10] [11] Enzyme degradation – proteins called enzymes break the neurotransmitters down. Reuptake – neurotransmitters are reabsorbed into the pre-synaptic neuron.
The GPCR can then activate an associated G-protein by exchanging its bound GDP for a GTP. The G-protein's α subunit, together with the bound GTP, can then dissociate from the β and γ subunits to further affect intracellular signaling proteins or target functional proteins directly depending on the α subunit type (G αs, G αi/o, G αq/11, G ...
Aerobic Exercise (Cardio): Physical activities like walking, running, swimming and cycling boost oxygen levels in the brain, which can support memory and cognitive function. Aim for at least 30 ...