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The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.
It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [ 1 ] [ 2 ] In 2022, the combination, calcium/vitamin D was the 246th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
Vitamin D receptor regulated genes involved in vitamin D metabolism are CYP27B1, which encodes the enzyme that produces active vitamin D. [209] [210] and CYP24A1, which encodes the enzyme responsible for degrading active vitamin D, [209] [210] In the area of calcium homeostasis and bone metabolism, several genes are regulated by vitamin D.
Calcium supplements, unlike calcium from dietary sources, appear to increase the risk of kidney stones. [1] Adults generally require about a gram of calcium a day. [1] Calcium is particularly important for bones, muscles, and nerves. [1] The medical use of calcium supplements began in the 19th century. [5]
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [3] to prevent and treat vitamin D deficiency [4] due to poor absorption by the intestines or liver disease. [5]
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