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There are several well known examples in primate chromosomes where the centromere position is different from the human centromere of the same chromosome and is thought to be evolutionary new centromeres. [37] Centromere repositioning and the formation of evolutionary new centromeres has been suggested to be a mechanism of speciation. [39]
A simple machine is a mechanical device that changes the direction or magnitude of a force. [1] In general, they can be defined as the simplest mechanisms that use mechanical advantage (also called leverage) to multiply force. [2] Usually the term refers to the six classical simple machines that were defined by Renaissance scientists: [3] [4 ...
However, the emergence of research in neocentromeres troubles this conventional definition and questions the function of a centromere beyond being a “landing pad” for kinetochore formation. [4] This expands the scope of the centromere's function to include regulating the function of the kinetochore and the mitotic spindle .
an inner kinetochore, which is tightly associated with the centromere DNA and assembled in a specialized form of chromatin that persists throughout the cell cycle; an outer kinetochore, which interacts with microtubules ; the outer kinetochore is a very dynamic structure with many identical components, which are assembled and functional only ...
Three types of cell division: binary fission (taking place in prokaryotes), mitosis and meiosis (taking place in eukaryotes).. When cells are ready to divide, because cell size is big enough or because they receive the appropriate stimulus, [20] they activate the mechanism to enter into the cell cycle, and they duplicate most organelles during S (synthesis) phase, including their centrosome.
During cell division, the identical copies (called a "sister chromatid pair") are joined at the region called the centromere (2). Once the paired sister chromatids have separated from one another (in the anaphase of mitosis) each is known as a daughter chromosome. The short arm of the right chromatid (3), and the long arm of the right chromatid ...
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Repeated sequences (also known as repetitive elements, repeating units or repeats) are short or long patterns that occur in multiple copies throughout the genome.In many organisms, a significant fraction of the genomic DNA is repetitive, with over two-thirds of the sequence consisting of repetitive elements in humans. [1]