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  2. Interferon beta-1b - Wikipedia

    en.wikipedia.org/wiki/Interferon_beta-1b

    Betaferon/Betaseron is marketed today by Bayer Pharma. The originator was Schering AG ( Berlex in North America), now part of Bayer Pharma. Novartis has also introduced Extavia, a new brand of interferon beta-1b, in 2009.

  3. Interferon beta-1a - Wikipedia

    en.wikipedia.org/wiki/Interferon_beta-1a

    Rebif is a disease-modifying drug (DMD) used to treat multiple sclerosis in cases of clinically isolated syndromes as well as relapsing forms of multiple sclerosis and is similar to the interferon beta protein produced by the human body. It is co-marketed by Merck Serono and Pfizer in the US under an exception to the Orphan Drug Act.

  4. Interferon - Wikipedia

    en.wikipedia.org/wiki/Interferon

    The superinduced human beta interferon messenger RNA was prepared by Tan's lab for Cetus. to clone the human beta interferon gene in bacteria and the recombinant interferon was developed as 'betaseron' and approved for the treatment of MS. Superinduction of the human beta interferon gene was also used by Israeli scientists to manufacture human ...

  5. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    For drugs that come in delayed release or time-release formulations, breaking the tablets or capsules can lead to more rapid delivery of the drug than intended. [25] The oral route is limited to formulations containing small molecules only while biopharmaceuticals (usually proteins) would be digested in the stomach and thereby become ineffective.

  6. Potency (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Potency_(pharmacology)

    For a response of 0.25a.u., Drug B is more potent, as it generates this response at a lower concentration. For a response of 0.75a.u., Drug A is more potent. a.u. refers to "arbitrary units". In pharmacology , potency or biological potency [ 1 ] is a measure of a drug's biological activity expressed in terms of the dose required to produce a ...

  7. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    5-HT 3 antagonists are most effective in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV), especially that caused by highly emetogenic drugs such as cisplatin; when used for this purpose, they may be given alone or, more frequently, with a glucocorticoid, usually dexamethasone.

  8. List of fentanyl analogues - Wikipedia

    en.wikipedia.org/wiki/List_of_fentanyl_analogues

    This is a list of fentanyl analogues (sometimes referred to as Fentalogs), [1] [2] [3] including both compounds developed by pharmaceutical companies for legitimate medical use, and those which have been sold as designer drugs and reported to national drug control agencies such as the DEA, or transnational agencies such as the EMCDDA and UNODC.

  9. Non-biological complex drugs - Wikipedia

    en.wikipedia.org/wiki/Non-biological_complex_drugs

    Even slight differences in manufacturing might result in therapeutic or safety differences not to be attributed to a known or defined component. The existing and defined biosimilar pathway , taking into consideration the complexity of biologics and its follow-on products, is neither applicable for NBCDs and its similars.

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