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Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
Conditions affecting the dorsal columns of the spinal cord, such as tabes dorsalis (neurosyphilis), in which it was first described. [1] Conditions affecting the sensory nerves (sensory peripheral neuropathies), such as chronic inflammatory demyelinating polyradiculoneuropathy . Friedreich's ataxia; Ménière's disease
Subacute combined degeneration of spinal cord; Diagram of the principal fasciculi of the spinal cord. (In subacute combined degeneration of spinal cord, the "combined" refers to the fact that the dorsal columns and lateral corticospinal tracts are both affected, in contrast to tabes dorsalis which is selective for the dorsal columns.)
Tabes dorsalis is a form of late neurosyphilis that affects the posterior columns of the spinal cord. Parenchymal syphilis occurs in the late stage of neurosyphilis, with average presentation occuring 15 to 25 years after initial infection. [3] This stage of the disease is generally in the form of tabes dorsalis or general paresis.
Abadie's sign of tabes dorsalis is a medical sign of tabes dorsalis, a late consequence of neurosyphilis. It is elicited by compressing the Achilles tendon , which normally causes pain. A positive Abadie's sign is defined by the absence of pain.
Hutchinson's mask is a patient's sensation that the face is covered with a mask or a gauzy network like cobwebs. This medical sign is associated with tabes dorsalis [1] affecting the trigeminal nerve (fifth cranial nerve CN V).
The bacteria Treponema pallidum that causes syphilis results in locomotor ataxia and tabes dorsalis. Further complications from tabes dorsalis include optic nerve damage, blindness, shooting pains, urinary incontinence, and degeneration of the joints. [6] In most cases, lesions present bilaterally.
It is often a symptom of tabes dorsalis, which is a key finding in tertiary syphilis. It is caused by degeneration of the posterior (dorsal) white column of the spinal cord. In popular culture