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Evidence that a standard A-Z multivitamin supplement will have much impact is scant, to say the least. ... and folate supplements (eg folic acid) for pregnant women. The reason for this last ...
However, the NHS recommends 10μg of Vitamin D per day throughout the pregnancy and while breastfeeding, and 400μg of folic acid during the first trimester (first 12 weeks of pregnancy). [15] Some women may need to take iron, vitamin C, or calcium supplements during pregnancy, but only on the advice of a doctor.
Doses of folic acid over 1 mg are prescription only. The amount of non-prescription prenatal vitamins needed to achieve this dose may have too much vitamin A and lead to fetal toxicity. [2] In addition, the U.S. Army currently provides female soldiers with optional prenatal supplements to combat high anemia rates in female soldiers. [10]
Folic acid, which is the synthetic form of the vitamin folate, is critical both in pre- and peri-conception. [7] Deficiencies in folic acid may cause neural tube defects (NTDs). Women who had 0.4 mg of folic acid in their systems due to supplementing 3 months before childbirth significantly reduced the risk of NTDs. [29]
It is recommended to accompany regular meals with a daily prenatal vitamin supplement that has sufficient folic acid and iron content. [30] If the fetus is predicted to have low birth weight, in addition to the general recommendations, it would be ideal to increase caloric intake, which can be done by having extra Food Guide Servings daily. [30]
In general, ULs are set for vitamins and minerals when evidence is sufficient. The adult UL of 1,000 μg for folate (and lower for children) refers specifically to folic acid used as a supplement, as no health risks have been associated with high intake of folate from food sources.
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