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Microcystic adnexal carcinoma (MAC) is a rare sweat gland cancer, [1] which often appears as a yellow spot or bump in the skin. It usually occurs in the neck or head, although cases have been documented in other areas of the body. Most diagnosis occur past the age of 50. Although considered an invasive cancer, metastasis rarely occurs.
The clinical quotes for cure rate of Mohs surgery are from 97% to 99.8% after 5 years for newly diagnosed basal-cell cancer (BCC), decreasing to 94% or less for recurrent basal-cell cancer. Radiation oncologists quote cure rates from 90 to 95% for BCCs less than 1 or 2 cm, and 85 to 90% for BCCs larger than 1 or 2 cm.
The diagnosis is made based on clinical and morphological features. Differential diagnosis includes trichoepithelioma, microcystic adnexal carcinoma, morpheaform basal cell carcinoma, and syringoma. Surgical excision is the treatment of choice. Desmoplastic trichoepithelioma is more common in females and usually affects children or adults.
Mohs surgery is also used for squamous-cell carcinoma, melanoma, atypical fibroxanthoma, dermatofibrosarcoma protuberans, Merkel cell carcinoma, microcystic adnexal carcinoma, and multiple other skin cancers; [47] [48] usually with cure rates higher than for other surgical and non-surgical treatments. [48]
Less common skin cancers include: Merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, porocarcinoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, keratoacanthoma, and skin sarcomas, such as angiosarcoma, dermatofibrosarcoma protuberans, Kaposi's sarcoma, leiomyosarcoma.
Microcystic adnexal carcinoma; M8408/0 Eccrine papillary adenoma (C44._) M8408/1 Aggressive digital papillary adenoma (C44._) M8408/3 Eccrine papillary adenocarcinoma ...
Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons. [ 1 ] : 670 Primary cutaneous adenoid cystic carcinomas have been misinterpreted as metastatic lesions. [ 2 ]
Porocarcinoma (PCA) (also termed malignant poroma, eccrine porocarcinoma, and malignant eccrine poroma) [1] is a rare form of skin cancer that develops in eccrine sweat glands, i.e. the body's widely distributed major type of sweat glands, as opposed to the apocrine sweat glands which are located primarily in the armpits and perineal area. [2]