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Microcystic adnexal carcinoma (MAC) is a rare sweat gland cancer, [1] which often appears as a yellow spot or bump in the skin. It usually occurs in the neck or head, although cases have been documented in other areas of the body. Most diagnosis occur past the age of 50.
The cure rate with Mohs surgery cited by most studies is between 97% and 99.8% for primary basal-cell carcinoma, the most common type of skin cancer. [2]: 13 Mohs procedure is also used for squamous cell carcinoma, but with a lower cure rate. Recurrent basal-cell cancer has a lower cure rate with Mohs surgery, more in the range of 94%.
Less common skin cancers include: Merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, porocarcinoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, keratoacanthoma, and skin sarcomas, such as angiosarcoma, dermatofibrosarcoma protuberans, Kaposi's sarcoma, leiomyosarcoma.
The diagnosis is made based on clinical and morphological features. Differential diagnosis includes trichoepithelioma, microcystic adnexal carcinoma, morpheaform basal cell carcinoma, and syringoma. Surgical excision is the treatment of choice. Desmoplastic trichoepithelioma is more common in females and usually affects children or adults.
Merkel cell carcinoma (cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, trabecular carcinoma of the skin) Microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) Micronodular basal cell carcinoma; Milia en plaque; Milium Milium; Mixed tumor (chondroid syringoma) Mucinous carcinoma
The nose and the temporal region are the most common areas of basal-cell carcinoma of the face. [62] When completely excised, the recurrence rate for basal-cell carcinoma is relatively low. However, when recurrence occurs among surgically treated basal-cell carcinomas of the face, there is a strong correlation with tumor thickness.
Microcystic adnexal carcinoma; M8408/0 Eccrine papillary adenoma (C44._) M8408/1 Aggressive digital papillary adenoma ... Fibrous papule of nose; Involuting nevus;
Frequently reported and reclassified over the last century, keratoacanthoma can be divided into various subtypes and despite being considered benign, their unpredictable behaviour has warranted the same attention as with squamous cell carcinoma. [1] Keratoacanthomas may be divided into the following types: [9]: 763–764 [10]: 643–646